UV SAFETY AWARENESS

4 Tips to Support Your Skin From the Inside Out

July is UV Safety Awareness Month, a reminder that protecting your skin matters most in the summer sun.
Sunscreen, shade, and protective clothing are your first line of defense, but nutrition can help, too.
This month, we’re sharing simple ways to care for your skin from the inside out.
Here are four tips to support your skin this summer:

Colorful foods to support skin health

1. Eat the rainbow for built-in UV defense

Carotenoids, pigments like beta-carotene and lycopene in carrots, sweet potatoes, tomatoes, and leafy greens,
accumulate in the skin and help neutralize UV-generated free radicals.
They don’t replace sunscreen, but they complement it.

Omega-3 rich foods for skin health

2. Prioritize omega-3s for skin resilience

Healthy fats in fatty fish, walnuts, flax, and chia help calm inflammation and may reduce the skin’s sensitivity
to UV-induced damage while supporting the skin barrier.

Polyphenol-rich foods

3. Load up on polyphenol-rich foods

Green tea, berries, extra-virgin olive oil, and dark leafy greens are packed with polyphenols that combat
the oxidative stress driving UV skin damage. An easy, delicious way to support your skin’s defenses.

Longevity Diet foods

4. Support your skin from the inside out with the Longevity Diet

These UV-protective nutrients come together naturally in the Longevity Diet’s mostly plant-based,
nutrient-dense pattern. Full of colorful vegetables, olive oil, nuts, and antioxidant-rich foods, these foods give
your skin a steady defense against oxidative stress while supporting long-term healthspan.
Paired with daily sunscreen, it offers protection from both outside and within.

BROCCOLI CONTAINS THE MOLEUCLE THAT PROTECTS AGAINST CANCER

Eating vegetables is good for health, and certain ones protect against cancer development. These include cruciferous plants like broccoli, cauliflower, cabbage, savoy cabbage, and brussels sprouts, whose beneficial properties have already been previously studied. A study analyzed how the reason why broccoli has protective properties against cancer is due to the presence of a molecule that is capable of turning off the gene involved in cancer onset. The study was carried out at the Harvard Medical School in Boston, USA, and published in May 2019 in the journal “Science”.

ANTI-CANCER ENZYME IDENTIFIED
This “magical” molecule is indoble-3 carbon (I3C). This natural substance can activate PTEN, a tumor suppressor gene that guards and protects cells against the WWP1 oncogene, an enzyme that can cause the onset of tumors wh. Ten in abundance. The researchers carried out the investigation in the laboratory using samples of human cells and mice models. Through biochemical analysis and computer simulations, they were able to identify the various molecules involved in the process. In particular, they observed how the I3C molecule found in crucifers is capable of turning on control systems against the growth and proliferation of cancer cells, such as the onco-suppressor PTEN.

The researchers managed to activate PTEN (“cell guardian”) by blocking WWP1 (“bad switch” that keeps PTEN turned off) specifically due to the I3C present in broccoli. This led to a size and weight reduction of the tumor. The study mainly focused on prostate cancer, but experts believe that the approach would show similar effects against other types of cancer, such as breast and liver cancer, where the WWP1 oncogene is very abundant.

FUTURE REASEARCH
The amount of broccoli that would be required to see these effects is 7 kg, but the study laid the foundation for new clinical trials that can look into developing the compound in its pure form at the pharmacological level. The molecules found in plants can serve as preventive methods in the fight against cancer.

SOURCES
Lee YR, Chen M, Pandolfi PP et Al. – Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway – Science (2019 May)

5 Tips to Start 2025

Our 5 Tips to Start Your Year

💭 Start with a Positive and Balanced Mind.

🚶🏻‍♂️ Step by Step

Gradually incorporate healthy habits, without rushing into strict routines. Sustainable progress comes with small steps, not extreme restrictions.

💦 Stay Hydrated

Keep your body well-hydrated by drinking plenty of water throughout the day. For added comfort, enjoy warm herbal teas—especially beneficial for those in colder climates.

🥗 More Vegetables

Make sure to include a generous portion of vegetables in your meals. This will provide essential vitamins, minerals, and fiber!

🚴🏻 Stay Active

Incorporate daily exercise, even if its just a walk. Take the stairs or add small activities to your routine. If youre into sports, ease back into your workouts gradually.

The Combined Effect of the “Longevity Diet” and Fasting Mimicking Diet Cycles (by Prof. Valter Longo)

Five years ago, a surgeon from Italy with diabetes and hypertension turned to my Foundation’s clinic. His endocrinologist had initially prescribed increasing doses of metformin, followed by two GLP-1 receptor agonist medications known for their weight-loss effects. These drugs, however, had little impact on his blood sugar levels or body weight, leading the Italian surgeon to resign himself to the prospect of the severe complications associated with diabetes. This was a fate I knew all too well, as kidney damage caused by diabetes had claimed the lives of two diabetic cousins I lived with after moving to Chicago.

With the endocrinologist’s consent, the Foundation’s nutritionists in Italy recommended the “Longevity Diet,” a predominantly vegan regimen with fish added 3-4 times per week. After nine months, the patient’s blood sugar and systolic blood pressure showed only slight improvements (from 140 to 133 mg/dL and 140 to 135 mmHg, respectively), and he continued taking medication. At that point, three 5-day cycles of the fasting mimicking diet were introduced.

Two randomized clinical trials—one conducted at Heidelberg University in Germany on 40 patients and another at Leiden University in the Netherlands on 100 patients—had shown reductions in blood sugar or medication usage in the majority of patients after 6-12 monthly fasting mimicking diet cycles. These cycles not only managed the disease but also led many patients toward disease reversal.

After just three fasting mimicking diet cycles within ten months, the Italian patient’s fasting glucose dropped to 90 mg/dL, and his systolic blood pressure to 120 mmHg, enabling doctors to discontinue his diabetes and hypertension medications. Eighteen months after starting the treatment, the patient was no longer a patient but a healthy individual, with the results still evident five years later. While the pescatarian diet led to a 3kg / 6.6 lbs weight loss in nine months, the three fasting mimicking diet cycles brought this total loss to 14 kg / 30.8 lbs. Interestingly, the Dutch study and others concluded that fasting mimicking diet’s effect on blood sugar is largely independent of weight loss.

Another significant, though not yet clinically confirmed, observation is that in the three years following his initial treatment, the Italian surgeon required only a few annual fasting mimicking diet cycles and a personalized Longevity Diet to maintain normal blood sugar and blood pressure levels. Larger studies are needed to confirm these results, but at least three additional clinical trials, beyond those mentioned above, suggest that fasting mimicking diet may impact blood sugar, fat mass, and blood pressure in diabetic and prediabetic patients.

This indicates that cycles of fasting mimicking diet and other innovative nutritional interventions have the potential to help doctors and nutritionists not only manage diabetes but treat it in certain patients. These approaches target rejuvenation mechanisms and reduce abdominal and liver fat, with additional effects on hypertension and kidney damage.

Prof. Valter Longo

DIABETES: WE CAN CURE IT AT THE TABLE

At the base of type 2 diabetes there are poor eating habits and an unhealthy lifestyle, which first lead to hyperglycemia, and then further lead up to chronic disease for which insulin therapy is necessary.

SCIENTIFIC RESEARCH EXPLAINS HOW TO REVERSE DIABETES WITH DIET

A clinical study, published in The Lancet Diabetes & Endocrinology (March 2019), examined how by changing the eating habits of patients with type 2 diabetes it is possible to reverse the disease. 300 patients were examined and followed for 2 years. These were overweight or obese subjects, with type 2 diabetes diagnosed for less than 6 years and not undergoing insulin therapy.

The study’s participants were divided into two groups. The first group received standard therapy, with insulin. The second group, on the other hand, did not receive drug therapy, but underwent nutritional changes. Specifi cally, for these diabetic patients, a low-calorie diet was provided, in which replacement meals were administered over 12-20 weeks. At the end of this first cycle of diet, in the following 2-8 weeks, the various foods were gradually reintroduced.

Clinical data for this group of patients undergoing calorie restriction showed a total remission of diabetes. Condition maintained in about 1 in 3 subjects, even in the two years following the end of the study. In practice, 11% of the individuals who had followed the low-calorie nutritional intervention maintained a reduction in body weight of at least 15 kg (30 lbs) and as many as 36% (more than 1 out of 3) benefited from a complete remission of diabetes, without having to take insulin therapy.

A further analysis of the data revealed that the percentage of remission of diabetic disease rose up to 64% in subjects who had maintained a decrease in body weight of at least 10 kg (20 lbs). This emphasizes how important it is to maintain a healthy weight to have lasting results.

THE SOLUTION TO CURE DIABETES IS FOR EVERYONE

This study highlights, once again, how important it is to follow a healthy and balanced diet, both for the prevention of diseases and for their treatment (with supplemental pharmacological therapies as needed). As far as type 2 diabetes is concerned, these are simple precautions to change your diet for the better. Easy to follow rules: reduce / eliminate simple sugars, favor the consumption of whole grains, respect the dose of proteins indicated for your daily intake, consume vegetables every day (limiting the high glycemic value). The best advice, for a diabetic person, is to be followed by an expert doctor or a nutritionist who can prepare a personalized diet for each individual case. Finally, exercise every day.

EFFECT OF DIET ON INTESTINE CANCER

Colorectal cancer is the third most common type of cancer in England, with about 23,000 diagnoses per year. Excessive consumption of red meat is one of the main causes. A study, conducted at the University of Oxford (UK), warns by showing that even a modest intake of red meat can increase the risk of intestine cancer incidence. The research results were published in the International Journal of Epidemiology (June 2019).

EVEN A LITTLE RED MEAT INCREASES THE INCIDENCE BY 20%

Previously, numerous scientifi c studies have already been conducted on the association of the development of bowel cancer and the consumption of red meat. Investigations mainly related to diets relating to the 90s and before. The new Oxford study (funded in part by Cancer Research UK) provides updated data and sheds light, with a more current view, on the dangers of red meat consumption today. The study monitored, for an average of 5.7 years (from 2006 to 2010) a sample of almost 500 thousand individuals of both sexes, aged between 40 and 69 years. Participants were asked to fi ll out questionnaires on how often they ate red meat, processed and otherwise. The results indicated that even small amounts of meat (be it roast beef, lamb, ham, bacon or other) consumed every day can increase the chance of developing bowel cancer by 20%. That is, of the 475,581 people who participated in the study, 2609 developed colon cancer.

FIBERS AND CEREALS DECREASE THE RISKS FOR INTESTINE CANCER

Data analysis revealed that subjects who reported an average consumption of 76 g (2.7 oz) per day of red and processed meat reported a 20% greater risk for colorectal cancer, compared to those who stated to consume 21 g (0.7 oz) per day. In particular, in regard to processed meat only, the risk of bowel cancer was greater than 19% in individuals who consumed an average of 29 g (1 oz) per day, compared to those who ate only 5 g (0.2 oz) per day. For unprocessed red meats, the risk was 15% higher in those who ate 54 grams per day, compared to those who ate only 8 g (0.3 oz) per day. An interesting fact refers to fi ber intake from bread and breakfast cereals. In this case, the participants had a 14% reduced risk of colorectal cancer. While the consumption of alcohol (for an intake exceeding 10 g/ 0.3 oz per day) was associated with an 8% greater risk. Fish, poultry, cheese, fruit, vegetables, tea and coffee, on the other hand, have not been associated with the risk of bowel cancer. The indication is to minimize the intake of red and processed meat, to no more than twice a week. Some experts recommend to completely eliminate red meat from our tables.

NEW CLINICAL STUDY ON THE COMBINATION BETWEEN FASTING MIMICKING DIET AND CHEMOTHERAPY

New research pairs fasting-mimicking diet with adjuvant chemotherapy in breast cancer patients. The study published in Nature Communications was conducted in several hospital centers in the Netherlands in collaboration with the research group of Professor Valter Longo. The results of this study add to the pre-clinical results and suggest, for the fi rst time in patients, that the fasting-mimicking diet is safe and effective in combination with chemotherapy in women with early-stage breast cancer.

FASTING-MIMICKING DIET AND VARIOUS STUDIES

Studies in mice have shown that fasting-mimicking diet cycles, in combination with a wide range of anti-cancer therapies, can protect against the side effects of chemotherapy, inhibit the progression of a wide variety of cancers and increase the therapeutic effi cacy of chemotherapy. There are also some clinical trials that have already evaluated the potential of fasting to improve cancer treatment, and that have mainly focused on patient feasibility and treatment toxicity. Proceeding in chronological order, the fi rst published study focuses on the collection by Professor Longo and his collaborators of data on ten people, who voluntarily chose to fast in conjunction with chemotherapy. The fi ndings suggest that fasting in combination with chemotherapy is feasible, safe, and has the potential to decrease the side effects caused by chemotherapy. The second study, by the University of Leiden, examined the feasibility of short-term fasting and its effects on the tolerance of chemotherapy in a homogeneous group of patients with ovarian or breast cancer. Fasting during chemotherapy was well tolerated and showed a reduction in side effects. A clinical study published by Professor Longo in 2016 saw 18 patients fast on water alone for 24, 48 or 72 hours before platinum-based chemotherapy, and was conducted to evaluate its safety and feasibility in cancer patients. The potential protective effects of 72-hour fasting compared to 24-hour fasting with breast, ovarian, uterus and lung cancer were visible. The last article studied the feasibility and effects on the quality of life and well-being of short-term fasting during chemotherapy in patients with gynecological cancer (ovary and breast). Short-term fasting during chemotherapy is well tolerated and appears to improve the quality of life and fatigue during the therapy itself.

WHAT IS NEW IN THIS STUDY

131 patients with stage II or III (HER2 negative) breast cancer were recruited for this study. 65 of these were asked to adopt a fasting-mimicking diet, starting 3 days before adjuvant chemotherapy. The remaining patients continued with their usual diet. Overall, these data are in agreement with previous studies, demonstrating that the fasting-mimicking diet is safe and effective in addition to chemotherapy, at least in patients with a normal body mass index at the time of enrollment. In addition, patients who followed the fasting-mimicking diet for multiple cycles of chemotherapy had improvements in radiological response and were more likely to decrease tumor cells by 90- 100%. In patients who have followed multiple fasting-mimicking diets, the damage induced by chemotherapy to the DNA of the T lymphocytes is signifi cantly reduced. It can be said that fasting has been shown to be safe in conjunction with chemotherapy treatments and has helped to reduce the adverse effects of the treatments themselves. However, new and more in-depth studies are needed to describe in detail the effect of the fasting-mimicking diet in this and other types of cancers. Currently, there are several clinical trials underway to verify the safety and effi cacy of the fasting-mimicking diet, particularly on the side effects of anti-cancer treatments and the enhancement of standard therapies. For more information about fasting and cancer, read Professor Longo’s last book Fasting Cancer (forthcoming in English).

PHYSICAL ACTIVITY AS ADULTS: IT’S NEVER TOO LATE

This is good news for those who never practiced sports as kids and want to start in older age. According to new scientific research conducted at the National Cancer Institute in Bethesda, Maryland, there are significant health benefits to exercising, even if starting in adulthood.

MOVING IS GOOD AT ANY AGE

This was shown by the results of the new American study published in the Jama JAMA Network Open in March 2019: playing sports or participating in physical activity is good for health, regardless of the age you start, whether it is during adolescence or adulthood. The beneficial effects range from a decreased risk of mortality linked to cardiovascular diseases and cancer, to decreased risk of infections in general. In this study, American researchers analyzed data from 315,000 adults aged between 50 and 70, and reviewed their habits and physical activity over different periods of life: as teenagers (15-18 years), young adults (35-39), and adults (40-61).

The data showed that the most active individuals (i.e. those who engaged in regular physical activity during each period of their life) presented a lower risk of all-cause mortality (cardio-vascular disease and cancer), compared to inactive individuals. In particular, those who practiced sports or physical activity since adolescence presented a lower risk of death, ranging between 29% and 36%. The striking data is that participants that were only active as adults (40-60 years), but sedentary during adolescence, also presented a lower risk of mortality of 32% to 35%, compared to individuals who were inactive throughout all stages of life.

SCIENTIFIC EVIDENCE OF THE BENEFITS OF PHYSICAL ACTIVITY

Previous studies have analyzed the benefits of physical activity carried out for a short period of time during adulthood, which is the primary and secondary prevention of cardiovascular diseases, respiratory disease, diabetes, cancer, neurological, and psychiatric problems. This was the first study to analyze how exercise can be associated with an increased risk of mortality at different stages of life. In fact, research carried out at the National Cancer Institute in Bethesda showed that starting to play sports or exercising as adults protects against the risk of cancer and cardiovascular diseases, similarly to having started at a young age. Now let’s get to those workouts!

SUGGESTIONS FOR THOSE 60+ yrs. old

What are the recommended activities and the amount of physical activity for those over 60? Here are the recommendations from the American Heart Association to prevent cardiovascular diseases: 30 minutes of moderate aerobic activity, 5 days a week, for a total of 150 minutes; 25 minutes of vigorous aerobic activity, 3 days a week, for a total of 75 minutes; a combination of moderate and vigorous aerobic activity; or moderate to intense muscle strengthening activity at least 2 days a week. In particular, to lower blood pressure and cholesterol levels, it’s recommended to do 40 minutes of moderate-intense aerobic activity, 3-4 times a week.

Among the most suitable physical activities are walking (preferably outdoors), swimming, cycling, postural gymnastics, and yoga. Running, in moderation, is also beneficial, as well as exercise in the gym to strengthen the muscles to improve endurance, and stretching to maintain flexibility.

SOURCES

  1. Pedro F. Saint-Maurice et Al. – Association of Leisure-Time Physical Activity Across the Adult Life Course With All-Cause and Cause-Specific Mortality – March 8, 2019 – JAM
  2. American Heart Association – Recommendations for Physical Activity in Adults and Kids

By Fondazione Valter Longo Onlus editorial staff
Fondazione Valter Longo Onlus aims to make scientific dissemination by raising awareness among the scientific and non-scientific community of a healthy lifestyle and proper nutrition through the production of explanatory scientific articles, textual, infographics and multimedia content, and the dissemination of clinical activities scientific, informative and educational aspects of the Foundation and its team of professionals. Dietary pathways, scientific discoveries, clinical studies, treatments and technologies, national and international awareness events, prevention initiatives as well as Longevity recipes are just some of the topics addressed in articles and in-depth interviews published daily and written in collaboration with the Foundation’s specialists. Also active on social networks, Fondazione Valter Longo Onlus editorial staff also offers a monthly newsletter sent to all members, to stay up to date on the most interesting news related to the world of Health, Nutrition and Longevity.
Contributors:
Romina Inés Cervigni
Alessandra Fedato
Maria Liliana Ciraulo
Corinna Montana Lampo
Cristina Villa
Contact: press@valterlongo.com or + 39 02 2513 8307

VITAMINS AND MINERALS FOR A HEALTHY IMMUNE SYSTEM

A well-balanced diet provides an adequate intake of micronutrients, ​vitamins and minerals​, that can ​boost our immune system​. Many studies point to their positive health effects, and specifically highlight the importance of ​vitamin C, D, and Zinc.
Vitamin C stimulates the body to increase its defenses against respiratory diseases. It’s found in citrus fruits (lemons, oranges), red fruits (currants and strawberries), kiwi, pineapple, cherries, watermelon, melon, and papaya. Green leafy vegetables are also rich in vitamin C: broccoli, cabbage, spinach, chard, turnip greens, rocket, lettuce, chicory, and parsley; as well as solanaceae like peppers and raw tomatoes.

Vitamin D also stimulates the immune system and prevents infections and lowers inflammation levels. 80% of it is obtained through sun exposure, while the other 20% is obtained from food. Foods rich in vitamin D are blue fish, such as mackerel, sardines, hering, anchovies, seas bass, tuna, salmon, and red mullet, as well as in eggs and mushrooms. Additionally, it can be found in dried fruits like almonds and walnuts, and in whole grains, beans, and green leafy vegetables.

Zinc plays an important role for the immune system: it promotes function of the thymus, especially against flu viruses, cooling symptoms, and bacterial infections of the respiratory tract. It is found mainly in shellfish and fish, whole grains, legumes (beans, lentils, chickpeas), dried fruit (almonds, walnuts, pine nuts, cashews and peanuts) and oilseeds (sesame, poppy, pumpkin and sunflower), as well as in mushrooms and cocoa.

Iron, Copper and Selenium​ also help us develop an efficient immune system.

Iron introduced in the diet is found in two forms: “heme” and “non-heme”. The first is present in animal products, such as liver, horse and beef red meats; as well as in blue fish (anchovies, sardines, anchovies, sea bass), seafood (clams, mussels and oysters), crustaceans, and egg (yolk). Non-heme iron, on the other hand, is present in plants and must be combined with vitamin C in order to be absorbed. Whole grains, legumes, especially lentils and beans, and green leafy vegetables, like rocket, spinach, parsley, and broccoli are rich in iron. Plums, raisins, apricots, and dates, as well as cashews and pistachios are good sources of iron. To best absorb it, it’s advised to combine these foods with vitamin C, such as lemon juice, tomatoes, peppers, and kiwis. Some substances, however, inhibit the absorption of iron: tea, coffee, chocolate, yogurt, cheese, and foods rich in calcium.
Copper stimulates the immune system since, in addition to promoting thyroid function, maintains an adequate amount of white blood cells, capable of fighting viruses and bacteria. It is found in molluscs, crustaceans, eggs, and meat, as well as in dried fruit (walnuts, almonds and hazelnuts), oilseeds (sunflower and pumpkin), legumes, whole grains, mushrooms, and cocoa.
Selenium​, along with vitamin C, stimulates the immune system’s defenses, and can protect individuals against flu viruses, infections and seasonal diseases. It’s found in blue fish, molluscs, eggs, dairy products and red meat. Additionally, selenium is found in plant sources such as whole grains, legumes, dried fruit, oilseeds, mushrooms and vegetables.

Other vitamins that are important for the immune system are vitamins A, E and B-vitamins.
Vitamin A​, in the form of retinol, along with carotenoids, acts as an antioxidant, boosts the immune system, and fights lung infections. The carotenoids are found in orange-red vegetables and fruits: carrots, squash, pepper tomatoes, apricots, peaches, melon, and medlars. As well as in green leafy vegetables and spices such as paprika. Retinol is found in blue fish, egg, yogurt, cheese and meat.
Vitamin E also helps support the immune system. It is found especially in dried fruit (almonds, hazelnuts and peanuts), oil seeds (sunflower, flax), green leafy vegetables, avocado, blackberries, chestnuts, olives and extra-virgin olive oil.
Finally we must mention the ​B-vitamins which are essential for the proper functioning of the immune system. They are found in fish, crustaceans, eggs, dairy products, meat, green leafy vegetables, whole grains, legumes, dried fruit, oilseeds. Vitamin B12 is found strictly in animal sources, so those who follow purely plant-based diets should consult a nutritionist for valid supplements that ward off their deficiency. Eating fish 2-3 times a week, together with legumes, many seasonal and possibly organic vegetables, whole grains and seasonal fruit, as suggested by the Longevity Diet, helps us give our body all the nutrients that it needs.

SOURCES

  1. https://www.mdpi.com/2073-4409/8/6/603​ -​https://www.mdpi.com/2072-6643/12/1/236/htm
  2. ​https://www.mdpi.com/2072-6643/12/1/236/htm
  3. https://www.ncbi.nlm.nih.gov/pubmed/28598721
  4. https://www.ncbi.nlm.nih.gov/pubmed/9587153
  5. https://www.ncbi.nlm.nih.gov/pubmed/30200430
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  7. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906676/pdf/nihms185109.pdf
  8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707683/
  9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266234/
  10. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478888/pdf/fnut-06-00048.pdf
  11. https://ods.od.nih.gov/factsheets/list-VitaminsMinerals/
  12. https://www.epicentro.iss.it/vitamine/
  13. https://www.epicentro.iss.it/vitamine/studi
  14. https://www.epicentro.iss.it/sali/
  15. https://www.epicentro.iss.it/sali/oligoelementi
  16. ​LARN – Livelli di assunzione di riferimento per la popolazione italiana: VITAMINE. Assunzione raccomandata per la popolazione (PRI) e assunzione adeguata (​AI​): valori su base giornaliera – Società Italiana di Nutrizione Umana-SINU, 2014

    LARN – Livelli di assunzione di riferimento per la popolazione italiana: MINERALI. Assunzione raccomandata per la popolazione (PRI) e assunzione adeguata (​AI​): valori su base giornaliera – Società Italiana di Nutrizione Umana-SINU, 2014

OBESE ADOLESCENTS RUN THE RISK OF HEART PROBLEMS LATER IN LIFE

Many scientific studies show that obesity and excess weight constitute risk factors for cardiovascular diseases. A study, conducted at the Sahlgrenska Academy of the University of Gothenburg, Sweden, identified a correlation between obesity during adolescence and the emergence of myocardial diseases in adulthood. The findings were published in the scientific journal Circulation (May 2019) of the American Heart Association.

CORRELATION BETWEEN EXCESSIVE WEIGHT and CARDIOMYOPATHY
Researchers analyzed a large pool of 1,668,893 Swedish males, between the ages of 18-19, and who had done their military service between 1969 and 2005. For these individuals, data regarding weight, height and BMI were taken from an official enrollment registry of that period. Then, two national databases were examined, analyzing the number of individuals admitted for treatment (and reasons) as well as the number deceased. The researchers’ aim was to determine whether the ex-military personnel suffered from heart disease as adults, through the age of 46.

The findings showed that 4,477 of these male youth later developed cardiomyopathy at the median age of 45.5. Cardiomyopathy is a disorder that strikes the myocardium and may result in insufficient heart function, and even sudden death. Cardiomyopathy is comprised of two forms: dilated and hypertrophic. In dilated cardiomyopathy, the heart weakens and can no longer pump blood. In hypertrophic cardiomyopathy, the heart grows rigid and cannot take in enough blood. In both cases, cardiac functioning is diminished and can result in cardiac insufficiency or heart failure.

WHAT THE FIINDINGS SHOW

This study underscores that individuals who were overweight as adolescents, with BMI equivalent to 34 (which corresponds to mid-range obesity) had 8 times the chance of developing dilated cardiomyopathy as adults. In contrast, the Swedish male subjects who were thin (BMI less than 20) at 18 years old had a low risk of developing cardiomyopathy. This risk, however, increased gradually as their body weight increased.

Of course, it should be noted that the study was limited to male youth, and, thus, applying the findings in a broader sense would require further and analogous studies of the female population.

By Corinna Montana Lampo

For further scientific data and information on the topic of healthy lifestyles and eating habits, visit the website of the Valter Longo Foundation, FONDAZIONE VALTER LONGO, where various clinical studies can be found.

SOURCES

  1. Annika Rosengren et Al. – Higher Body Mass Index in Adolescence Predicts Cardiomyopathy Risk in Midlife, Long-Term Follow-Up Among Swedish Men – Circulation (May 2019)
  2. American Heart Association – Hearth News Being overweight as a teen may be associated with higher risk of heart muscle disease in adulthood – Circulation Journal Report (data ultimo accesso 01.08.2019)

WHAT TO EAT BEFORE AND AFTER PHYSICAL ACTIVITY

Consuming a healthy and balanced diet, and exercising regularly are among the foundations for living a long and healthy life, as well as contributing factors to overall wellbeing. The body needs energy to carry out daily activities or during sports and physical activity. What are the ideal foods to consume before and after a workout to ensure the greatest benefits?

WHAT TO EAT BEFORE EXERCISING
First of all, it is essential to eat properly before doing any physical activity. Exercising in a fasted state can cause hypoglycemia and hunger spikes, it increases the risk of fainting, and may even result in a muscle catabolism process that may put toxins in the bloodstream. Food taken in before playing sports or any other physical activity, even walking to work, is important because it is the body’s source of energy during these activities.

In general, nutritionists recommend a simple and light pre-workout meal (to avoid complex and prolonged digestion) with an adequate amount of nutrients, to ensure the right energy and nutritional intake. If you practice sports in the morning, for example, it’s recommended to have a quick snack before physical activity, and then have a rich and complete breakfast afterwards. Lunch should be consumed at least 3 hours prior to exercising to make sure it doesn’t affect the digestive process, and should be based on carbohydrates with a low glycemic index, such as whole grains and vegetables, and with minimal protein and fat to enhance both strength and endurance. If you exercise in the evening, have a snack (banana, walnuts, granola bar) about 2 hours before working out.

WHAT TO EAT AFTER EXERCISING
First of all, never skip a meal after physical activity. Nutritionists recommend consuming 30 grams of protein within 1-2 hours after each workout. Protein is essential for muscle recovery, and helps regenerate muscle fibers after physical activity. In fact, athletes should always consume healthy amounts of protein from various sources, such as fish, legumes, whole grains, and dairy products. Fats are also important for those who exercise, especially healthy fats like vegetable oil, dried fruits, nuts, and seeds. After exercising, the body gets rid of toxins and must replenish energy reserves, as well as restore damaged muscle tissue.

In the 15-30 minutes post-workout, the muscles are able to quickly absorb nutrients to synthesize new tissue and repair the damage caused by physical activity. This time frame is called the “anabolic window” (which gradually decreases within 2 hours), and some nutritionists recommend eating a protein snack immediately after a workout to regenerate the muscles. This is especially true for those who play sports at an intermediate to professional level. For those who simply want to lose weight and/or maintain a healthy weight, it is still recommended to take advantage of the increased basal metabolic rate and eat 1 or 2 hours after exercising. In any case, it is good to consult a nutritionist to evaluate your situation and choose an appropriate diet.

THE IMPORTANCE OF HYDRATION
Another fundamental issue is hydration: replenishing fluids lost during physical activity, especially on hot and sunny days. The risk we face is dehydration which, in addition to decreasing athletic performance, can be harmful to the body. It’s advised to drink water before, during, and after training, to replenish the liquids lost during the workout. If necessary, it can be useful to consume water rich in mineral salts and/or saline supplements in moderation.

SOURCES

    1. Arem H. et Al., “Leisure time physical activity and mortality: a detailed pooled analysis of the dose-response relationship”, JAMA Intern Med. 2015 Jun;175(6):959-67. doi: 10.1001/jamainternmed.2015.0533
    2. Paddon-Jones D, Rasmussen BB. “Dietary protein recommendations and the prevention of sarcopenia” Curr Opin Clin Nutr Metab Care – 2009 Jan;12(1):86-90. doi: 10.1097/MCO.0b013e32831cef8b

 

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By Fondazione Valter Longo Onlus editorial staff
Fondazione Valter Longo Onlus aims to make scientific dissemination by raising awareness among the scientific and non-scientific community of a healthy lifestyle and proper nutrition through the production of explanatory scientific articles, textual, infographics and multimedia content, and the dissemination of clinical activities scientific, informative and educational aspects of the Foundation and its team of professionals. Dietary pathways, scientific discoveries, clinical studies, treatments and technologies, national and international awareness events, prevention initiatives as well as Longevity recipes are just some of the topics addressed in articles and in-depth interviews published daily and written in collaboration with the Foundation’s specialists. Also active on social networks, Fondazione Valter Longo Onlus editorial staff also offers a monthly newsletter sent to all members, to stay up to date on the most interesting news related to the world of Health, Nutrition and Longevity.
Contributors:
Romina Inés Cervigni
Alessandra Fedato
Maria Liliana Ciraulo
Corinna Montana Lampo
Cristina Villa
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