The FMD and Cardiovascular Diseases, Results of Clinical Trials, Prevention, and Treatment
For more detailed information about the FMD, prevention, and treatment of cardiovascular diseases, see Chapter 9, The Longevity Diet (New York: Avery/Penguin Books, 2018).
In our human clinical study involving 100 participants, FMD cycles affected many of the major risk factors or markers contributing to or associated with cardiovascular diseases, particularly in individuals at high risk. The results of the FMD related to cardiovascular diseases include the following:
- Reduced abdominal fat and circumference
- Major drop in the inflammatory risk factor, C-reactive protein
- Reduction in total and LDL cholesterol
- Lowering of triglycerides
- Reduction in systolic and diastolic blood pressure
- Reduction in fasting glucose

C-Reactive Protein, Blood Pressure, and LDL Cholesterol, All Risk Factors for Cardiovascular Disease, Decreases After Three Cycles of the FMD




Prevention
- Follow the Longevity Diet (see Chapter 4, The Longevity Diet, “How to Stay Young—Everyday Diet”) and exercise guidelines (see Chapter 5, “How to Stay Young—Exercise and Longevity”).
- Undergo periodic fasting-mimicking diets. For very healthy individuals with no cardiovascular disease risk factors, we recommend FMD once every six months. For those overweight with multiple risk factors for cardiovascular diseases, including a family history of heart disease or stroke, we recommend FMD once a month until normal weight is achieved, after which it can be reduced according to the guidelines in Chapter 6.
